Be aware of the background
A plain background shows off the art you are photographing. When you look through the camera viewfinder, force yourself to study the area surrounding your subject. Make sure no carpet, tiles, or any other distracting background is showing. Also by default the image is always portrait so try landscape mode so that only subject is captured.
Move in Close
Your goal is to fill the picture area with the artwork you are photographing. Up close you can reveal telling details.But don't get too close or your pictures will be blurry.
Avoid holding it
Try to avoid holding the creation in your hands. Keep the subject the focus so there are no hands or other background showing. Ideally place the artwork on a flat dark or white background and click it that way the masterpiece remains the main subject! Also holding it sometime creates weird angles and can look really bad when you are ready to print.
Use The Image Crop Feature
If you do end up taking the photo showing background then just use the image crop feature to crop the background out and bring the focus back to the artwork.
Choose good lighting
Pick a room with good lighting or use the flash option so there are no shadows showing on the artwork.